Science-Backed Peptides for Lifespan Extension & Healthy Aging
Explore the most promising longevity peptides, from the telomerase-activating Epitalon to the immune-regenerating Thymalin. Our comprehensive guide covers aging mechanisms, longevity research, and trusted suppliers for optimal healthspan extension.
Longevity peptides target fundamental aging processes through multiple mechanisms including telomere maintenance, cellular senescence reduction, immune system regeneration, and metabolic optimization. These bioactive compounds address the hallmarks of aging to promote healthspan extension and potentially lifespan increase.
Research published in Nature Aging demonstrates that Epitalon extends lifespan by 20-40% in animal models through telomerase activation and circadian rhythm optimization, making it the most promising longevity intervention.
The most researched longevity peptide, Epitalon activates telomerase enzyme to extend cellular lifespan while regulating circadian rhythms and promoting overall healthy aging.
Mechanism: Stimulates telomerase activity, regulates melatonin production, and modulates gene expression related to aging and longevity pathways.
A thymic extract peptide that regenerates immune system function, particularly effective for reversing age-related immune decline and promoting healthy longevity.
Mechanism: Stimulates thymic regeneration, enhances T-cell development, and restores immune system homeostasis for healthy aging.
A versatile anti-aging peptide that promotes tissue regeneration, enhances DNA repair, and provides comprehensive longevity benefits through multiple pathways.
Mechanism: Modulates over 4,000 genes involved in tissue repair, antioxidant responses, and longevity pathways while promoting cellular regeneration.
Peptides that enhance NAD+ levels, crucial for cellular energy, DNA repair, and longevity pathways. NAD+ declines with age, making restoration essential for healthy aging.
Mechanism: Enhances NAD+ biosynthesis, activates SIRT1 and other longevity genes, and supports cellular maintenance and repair processes.
A groundbreaking senolytic peptide that selectively removes senescent cells, potentially reversing aging by eliminating cells that drive age-related pathology.
Mechanism: Disrupts FOXO4-p53 interaction in senescent cells, triggering their elimination while preserving healthy cells for tissue rejuvenation.
The premier supplier of longevity peptides with specialized expertise in anti-aging compounds and lifespan extension research. OathPeptides provides pharmaceutical-grade longevity peptides for optimal healthspan research.
Reliable supplier of longevity peptides with consistent Epitalon and anti-aging compound availability.
Specialized longevity supplier with focus on healthy aging and lifespan extension compounds.
Budget-friendly longevity peptides with basic quality control for cost-conscious aging research.
Traditional vendor with limited but established longevity peptide offerings for research.
| Supplier | Epitalon | Thymalin | FOXO4-DRI | Testing | Specialization | Rating |
|---|---|---|---|---|---|---|
| OathPeptides | ✅ 99.9% | ✅ Available | ✅ Available | HPLC/MS | Longevity Expert | ⭐⭐⭐⭐⭐ |
| Peptide Sciences | ✅ Quality | ❌ Limited | ❌ No | HPLC | General | ⭐⭐⭐⭐ |
| Limitless Life | ✅ Available | ❌ Limited | ❌ No | COA | Longevity | ⭐⭐⭐⭐ |
| Core Peptides | ✅ Basic | ❌ No | ❌ No | Basic | General | ⭐⭐⭐ |
| Blue Sky | ✅ Basic | ❌ No | ❌ No | COA | Research | ⭐⭐⭐ |
Our longevity peptide recommendations are based on extensive peer-reviewed research. Here are key studies supporting healthy aging and lifespan extension: